The DEMs targeted by DEMIs were identified and the negative correlation between DEMs and DEMIs was subjected to visualization.
The potential functions of DEMs targeted by DEMIs were annotated in Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) database.
A total of 663 dysregulated DEMs (449 upregulated and 214 downregulated) and 33 DEMIs (24 upregulated and 8 downregulated) were identified in LSCC compared with normal controls.
502 negative correlations between DEMIs and DEMs were identified and subjected to construct interaction network.